OlfTrans

Olfactory Transduction Utilities for FlyBrainLab.

Features

The main features of the package are 3 fold:

  1. Estimating Binding and Dissociation Rates from Data (see next session for available datasets)

  2. Running OTP-BSG Cascades

  3. Working with other FlyBrainLab libraries

Datasets

OlfTrans relies on the following datasets to estimate model parameters for Drosophila adult and larva Odorant Transduction:

  1. (Included) Hallem, E. A., & Carlson, J. R. (2006). Coding of Odors by a Receptor Repertoire. Cell. DOI1

    • Accessible as olftrans.data.HallemCarlson

  2. (Included) Kreher, S. A., Kwon, J. Y., & Carlson, J. R. (2005). The molecular basis of odor coding in the Drosophila larva. Neuron. DOI2

    • Accessible as olftrans.data.Kreher

  3. (Need Download) Lazar, A. A., & Yeh, C.-H. (2020). A molecular odorant transduction model and the complexity of spatio-temporal encoding in the Drosophila antenna. PLOS Computational Biology. DOI3

    • Electrophysiology data of Drosophila adult antenna can be downloaded here

    • Rename the downlaod the file (77 MB) as antenna_data.h5 and place into the olftrans/data/ folder

    • Afterwards, accessible as olftrans.data.Physiology

Credits

This package was created with Cookiecutter and the audreyr/cookiecutter-pypackage project template.

Many Utilities/Plotting functions are adapted from Neural.